The film, set in 1892, stars Bale as a captain who agrees to escort a dying Cheyenne war chief (Wes Studi) and his family back home to tribal lands. The journey takes Bale and his detail from New Mexico to the grasslands of Montana.

Along the way they pick up a young widow (Pike), whose family has been murdered on the plains by hostile Comanche natives. Jesse Plemons, Rory Cochrane, Ben Foster, Jonathan Majors and Timothee Chalamet also star.